Injecting regulatory T cells, which are responsible for controlling immune responses, directly into damaged tissues such as bones, muscles and skin can significantly enhance the healing process, according to a new study. The report was published on the New Atlas website, citing the Nature Communications journal, and explained that this method may represent a turning point in the development of new treatments that enhance recovery after injuries.
The study, conducted by researchers from the University of Cambridge, showed that regulatory T cells could be used as a powerful treatment force for a variety of infections. Despite their great potential, research on the use of these cells has been limited so far.
White blood cells, including regulatory T cells, are essential in fighting infections and cleaning up damaged cells. Research has shown that moving from an active inflammatory state to an anti-inflammatory state is necessary for healing. Therefore, regenerative medicine treatments aim to take advantage of these cells.
In the study, researchers injected a hydrogel containing regulatory T cells into injured tissues of lab mice, including skull defects, muscle loss, and skin wounds. The examination showed that the mice that received these cells showed a significant improvement in the healing of bone and muscle tissue, as well as faster wound healing.
Shizuo Akira, one of the lead researchers, explained that the treated mice showed an increase in bone size and the amount of muscle tissue. When analyzing the mechanisms, it was found that regulatory T cells interacted specifically with the affected areas, leading to enhanced healing.
Mikael Martino from Monash University also pointed out that regulatory T cells can influence other types of immune cells and promote the secretion of signaling molecules that are important for the healing process. He emphasized that the IL-10 molecule plays a key role in supporting these cells in the regeneration process.
The results of this study demonstrate the promising potential of using regulatory T cells as a regenerative medical therapy after tissue injuries. Although the research focused on the effect of these cells when given immediately after injury, future studies will seek to determine the optimal timing for their use to ensure their effectiveness in recovery.
صحافة بلادي صحيفة إلكترونية مغاربية متجددة على مدار الساعة تعنى بشؤون المغرب الجزائر ليبيا موريتانيا تونس